Our current projects range from post-translational protein modifications, drug screening for neurodegenerative diseases to the synthesis of bioconjugates using nanomaterials.
Biosensing neurodegenerative diseases:
Alzheimer’s disease is the principal cause of senile dementia. The fibrillation of amyloid-β peptides is investigated using electrochemical and optical techniques. The effect of metal ions on the fibrillation process of the peptides sheds a light on the development of possible therapeutics.
Bioconjugates of nanoparticles
Carbon nanotubes, metal nanoparticles, and quantum dots are conjugated with aptamers and lectins for the detection of biochemical events on solid surfaces.
Biosensors for environmental monitoring
Disposable biosensors are developed for the on-field determination of environmentally hazardous compounds and bacteria. Enzymes, nucleic acids, and peptides are used as the biorecognition layers on solid surfaces.